CBD can have an interaction with certain drugs in a manner that is similar to grapefruit. Research has shown that certain compounds in grapefruit can interact with many common pharmaceutical drugs by inhibiting cytochrome P450 enzymes, a family of liver enzymes that metabolizes these drugs. However, CBD can also inhibit these enzymes when consumed at high enough dosages.
We always recommend checking with your physician before starting a new dietary supplement program. Any instructions you may have received from a medical professional regarding grapefruit should be treated with the same level of care when it comes to CBD products.